ABECMA

This brand name is authorized in Austria, Canada, Cyprus, Estonia, France, Croatia, Ireland, Italy, Lithuania, Poland, United States

Active ingredients

The drug ABECMA contains one active pharmaceutical ingredient (API):

1 Idecabtagene vicleucel UNII 8PX1X7UG4D - IDECABTAGENE VICLEUCEL

Idecabtagene vicleucel is a chimeric antigen receptor (CAR)-positive T cell therapy targeting B-cell maturation antigen (BCMA), which is expressed on the surface of normal and malignant plasma cells. The CAR construct includes an anti-BCMA scFv-targeting domain for antigen specificity, a transmembrane domain, a CD3-zeta T cell activation domain, and a 4-1BB costimulatory domain. Antigen-specific activation of idecabtagene vicleucel results in CAR-positive T cell proliferation, cytokine secretion and subsequent cytolytic killing of BCMA-expressing cells. Read about Idecabtagene vicleucel

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ABECMA Dispersion for infusion	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01XL07		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XL Antineoplastic cell and gene therapy
Discover more medicines within L01XL07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: CA	Health Products and Food Branch	Identifier(s): 02516233
Country: EE	Ravimiamet	Identifier(s): 1860140
Country: FR	Base de données publique des médicaments	Identifier(s): 65329132
Country: IT	Agenzia del Farmaco	Identifier(s): 049604010
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1093238
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100457776
Country: US	FDA, National Drug Code	Identifier(s): 59572-515