ACIGESTOL

Bismuth subsalicylate is a derivative of salicylic acid, with anti-inflammatory and bactericidal action. Bismuth subsalicylate has weak antacid properties. Bismuth subsalicylate is used as an antacid and antidiarrheal, and to treat temporary discomfort of the stomach and gastrointestinal tract, such as nausea, heartburn, indigestion, upset stomach, and diarrhea. Bismuth subsalicylate may exert its antidiarrhoeal action not only by stimulating absorption of fluid and electrolytes across the intestinal wall but also when hydrolysed to salicylic acid, by inhibiting synthesis of a prostaglandin responsible for intestinal inflammation and hypermotility.