ACTIKERALL

This brand name is authorized in Austria, Canada, Estonia, Spain, Finland, Lithuania, Mexico, Poland, United Kingdom

Active ingredients

The drug ACTIKERALL contains a combination of these active pharmaceutical ingredients (APIs):

1 Fluorouracil
UNII U3P01618RT - FLUOROURACIL

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine – which become the building blocks of DNA. They prevent these substances from becoming incorporated into DNA during the “S” phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand. Fluorouracil is used for the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, esophageal, gastric, rectum, breast, biliary tract, stomach, head and neck, cervical, pancreas, renal cell, and carcinoid.

Read about Fluorouracil
2 Salicylic acid
UNII O414PZ4LPZ - SALICYLIC ACID

Salicylic acid has bacteriostatic and fungicidal actions, but it is its keratolytic properties which are important for this medicinal product. When applied externally it produces slow and painless destruction of the epithelium.

Read about Salicylic acid

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
ACTIKERALL Cutaneous solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01BC52 Fluorouracil, combinations L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BC Pyrimidine analogues
Discover more medicines within L01BC52

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: CA Health Products and Food Branch Identifier(s): 02428946
Country: EE Ravimiamet Identifier(s): 1552014, 1848731
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 77675
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 599927
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 191861
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1064301
Country: MX Comisión Federal para la Protección contra Riesgos Sanitarios Identifier(s): 233M2012
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100280775

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.