ADEMPAS

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States

Active ingredients

The drug ADEMPAS contains one active pharmaceutical ingredient (API):

1 Riociguat UNII RU3FE2Y4XI - RIOCIGUAT

Riociguat is a stimulator of soluble guanylate cyclase (sGC), an enzyme in the cardiopulmonary system and the receptor for nitric oxide (NO). Riociguat restores the NO-sGC-cGMP pathway and leads to increased generation of cGMP. Read about Riociguat

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ADEMPAS Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
C02KX05		C Cardiovascular system → C02 Antihypertensives → C02K Other antihypertensives → C02KX Antihypertensives for pulmonary arterial hypertension
Discover more medicines within C02KX05

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 10974N, 10975P, 10976Q, 10977R, 10984D, 10985E, 10989J, 10990K, 10995Q, 11001B, 11002C, 11008J, 11009K, 11010L, 11012N, 11013P, 11017W, 11018X, 11019Y, 11020B, 11024F, 11028K, 11030M, 11031N, 11035T, 11038Y, 11039B, 11040C, 11045H, 11046J, 11047K, 11048L, 11052Q, 11053R, 11054T, 11057Y, 11058B, 11059C, 11060D, 11061E
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 538916010025301, 538916010025501, 538916010025701, 538916010025801, 538916010025901, 538916010026001, 538916010026101, 538916010026201
Country: CA	Health Products and Food Branch	Identifier(s): 02412764, 02412772, 02412799, 02412802, 02412810
Country: EE	Ravimiamet	Identifier(s): 1644375, 1644386, 1644397, 1644409, 1644410, 1644421, 1644432, 1644443, 1644454, 1644465, 1644476, 1644487, 1644498, 1644500, 1644511, 1699735, 1699746, 1699757, 1699768, 1699779
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 113907004, 113907007, 113907010, 113907013
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 069347, 112191, 135090, 164827, 165799, 415368, 485304, 541846, 561780
Country: FR	Base de données publique des médicaments	Identifier(s): 60025054, 60203795, 61875550, 64832942, 66086562
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 243980, 243985, 243994, 243998, 243999, 244007, 244009
Country: HK	Department of Health Drug Office	Identifier(s): 63505, 63509, 63510, 63511, 63512
Country: IE	Health Products Regulatory Authority	Identifier(s): 88599, 88690, 88692, 88694, 88695, 89068, 89069
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 7574, 7575, 7578, 7768
Country: JP	医薬品医療機器総合機構	Identifier(s): 2190034F1027, 2190034F2023, 2190034F3020
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1073042, 1073043, 1073044, 1073045, 1073046, 1073047, 1073048, 1073049, 1073050, 1073051, 1073052, 1073053, 1073054, 1073055, 1073056, 1074977, 1074978, 1074979, 1074980, 1074981
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 124656, 124664, 124672, 124680, 124699
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 16951, 16952, 16953, 16954, 16955
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100322670, 100322686, 100322692, 100322700, 100322717
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W63713001, W63714001, W63715001, W63716001, W63717001
Country: SG	Health Sciences Authority	Identifier(s): 14678P, 14679P, 14680P, 14681P, 14682P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699546090198, 8699546090204, 8699546090211, 8699546090228, 8699546090235, 8699546090242, 8699546090266, 8699546090273, 8699546090280, 8699546090297
Country: US	FDA, National Drug Code	Identifier(s): 50419-250, 50419-251, 50419-252, 50419-253, 50419-254