ADVAGRAF

This brand name is authorized in Albania, Australia, Austria, Canada, Croatia, Cyprus, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Italy, Lithuania, Netherlands, Poland, Romania, Singapore, South Africa, Spain, Tunisia, Turkey, UK.

Active ingredients

The drug ADVAGRAF contains one active pharmaceutical ingredient (API):

1	Tacrolimus UNII WM0HAQ4WNM - TACROLIMUS
	Tacrolimus is a highly potent immunosuppressive agent. In particular, tacrolimus inhibits the formation of cytotoxic lymphocytes, which are mainly responsible for graft rejection. Tacrolimus suppresses T-cell activation and T-helper-cell dependent B-cell proliferation, as well as the formation of lymphokines (such as interleukins-2, -3, and γ-interferon) and the expression of the interleukin-2 receptor.
	Read more about Tacrolimus

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L04AD02	Tacrolimus	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AD Calcineurin inhibitors
Discover more medicines within L04AD02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AL	Fondi i Sigurimit të Detyrueshëm të Kujdesit Shëndetësor	452/191a
AU	Pharmaceutical Benefits Scheme	11907Q, 11914C, 11920J, 5299X, 5300Y, 5451X, 9664P, 9665Q, 9666R, 9681M, 9682N, 9683P
CA	Health Products and Food Branch	02296462, 02296470, 02296489, 02331667
EE	Ravimiamet	1294635, 1294646, 1294657, 1294668, 1294679, 1294680, 1294691, 1294703, 1362484, 1362495, 1488326, 1488337, 1488348
ES	Centro de información online de medicamentos de la AEMPS	07387014, 07387017, 07387019, 07387021, 07387024
FI	Lääkealan turvallisuus- ja kehittämiskeskus	094287, 182307, 389944, 484721, 572422
FR	Base de données publique des médicaments	61604257, 61727612, 63931834, 64297436
GB	Medicines & Healthcare Products Regulatory Agency	116193, 116197, 116198, 116201, 140514, 140517, 156041, 196917
HK	Department of Health Drug Office	56594, 56595, 56596
IE	Health Products Regulatory Authority	88004, 88012, 88023, 88444
IL	מִשְׂרַד הַבְּרִיאוּת	7670, 7671, 7672, 7673
IT	Agenzia del Farmaco	038218018, 038218057, 038218071, 038218119
LT	Valstybinė vaistų kontrolės tarnyba	1026420, 1026421, 1026422, 1026423, 1026424, 1026425, 1026426, 1037729, 1037730, 1037731, 1060782, 1060783, 1060784, 1060785, 1060786, 1060787, 1060788, 1060789, 1060790, 1060791, 1060792, 1060793, 1060794, 1068375, 1070822, 1070823
NL	Z-Index G-Standaard, PRK	96148, 96156, 96164, 96172
PL	Rejestru Produktów Leczniczych	100013229, 100042716, 100075615, 100209151
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W51974002, W51974004, W51976002, W51976004, W57352002, W57352005
SG	Health Sciences Authority	14133P, 14134P, 14135P
TN	Direction de la Pharmacie et du Médicament	6653661H, 6653662H, 6653663H
TR	İlaç ve Tıbbi Cihaz Kurumu	8699043890178, 8699043890185, 8699043890192, 8699043890208, 8699043890215, 8699043890222, 8699043890239, 8699043890246, 8699043890253, 8699043890260, 8699043890406, 8699043890437, 8699043890444
ZA	Health Products Regulatory Authority	42/34/0787, 42/34/0788