ADVAGRAF

This brand name is authorized in Albania, Austria, Australia, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Lithuania, Netherlands, Poland, Romania, Singapore, Tunisia, Turkey, United Kingdom, South Africa

Active ingredients

The drug ADVAGRAF contains one active pharmaceutical ingredient (API):

1 Tacrolimus UNII WM0HAQ4WNM - TACROLIMUS

Tacrolimus is a highly potent immunosuppressive agent. In particular, tacrolimus inhibits the formation of cytotoxic lymphocytes, which are mainly responsible for graft rejection. Tacrolimus suppresses T-cell activation and T-helper-cell dependent B-cell proliferation, as well as the formation of lymphokines (such as interleukins-2, -3, and γ-interferon) and the expression of the interleukin-2 receptor. Read about Tacrolimus

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L04AD02	Tacrolimus	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AD Calcineurin inhibitors
Discover more medicines within L04AD02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AL	Fondi i Sigurimit të Detyrueshëm të Kujdesit Shëndetësor	Identifier(s): 452/191a
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 11907Q, 11914C, 11920J, 5299X, 5300Y, 5451X, 9664P, 9665Q, 9666R, 9681M, 9682N, 9683P
Country: CA	Health Products and Food Branch	Identifier(s): 02296462, 02296470, 02296489, 02331667
Country: EE	Ravimiamet	Identifier(s): 1294635, 1294646, 1294657, 1294668, 1294679, 1294680, 1294691, 1294703, 1362484, 1362495, 1488326, 1488337, 1488348
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 07387014, 07387017, 07387019, 07387021, 07387024
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 094287, 182307, 389944, 484721, 572422
Country: FR	Base de données publique des médicaments	Identifier(s): 61604257, 61727612, 63931834, 64297436
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 116193, 116197, 116198, 116201, 140514, 140517, 156041, 196917
Country: HK	Department of Health Drug Office	Identifier(s): 56594, 56595, 56596
Country: IE	Health Products Regulatory Authority	Identifier(s): 88004, 88012, 88023, 88444
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 7670, 7671, 7672, 7673
Country: IT	Agenzia del Farmaco	Identifier(s): 038218018, 038218057, 038218071, 038218119
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1026420, 1026421, 1026422, 1026423, 1026424, 1026425, 1026426, 1037729, 1037730, 1037731, 1060782, 1060783, 1060784, 1060785, 1060786, 1060787, 1060788, 1060789, 1060790, 1060791, 1060792, 1060793, 1060794, 1068375, 1070822, 1070823
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 96148, 96156, 96164, 96172
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100013229, 100042716, 100075615, 100209151
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W51974002, W51974004, W51976002, W51976004, W57352002, W57352005
Country: SG	Health Sciences Authority	Identifier(s): 14133P, 14134P, 14135P
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 6653661H, 6653662H, 6653663H
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699043890178, 8699043890185, 8699043890192, 8699043890208, 8699043890215, 8699043890222, 8699043890239, 8699043890246, 8699043890253, 8699043890260, 8699043890406, 8699043890437, 8699043890444
Country: ZA	Health Products Regulatory Authority	Identifier(s): 42/34/0787, 42/34/0788