This brand name is authorized in Germany
The drug ANTILIA contains a combination of these active pharmaceutical ingredients (APIs):
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1
Rosuvastatin
UNII 83MVU38M7Q - ROSUVASTATIN CALCIUM
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Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles. |
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2
Ezetimibe
UNII EOR26LQQ24 - EZETIMIBE
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Ezetimibe is in a new class of lipid-lowering compounds that selectively inhibit the intestinal absorption of cholesterol. The molecular target of ezetimibe is the sterol transporter, Niemann-Pick C1-Like 1 (NPC1L1), which is responsible for the intestinal uptake of cholesterol. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10BA06 | C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BA Combinations of various lipid modifying agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: DE | Bundesinstitut fĂźr Arzneimittel und Medizinprodukte | Identifier(s): 14143795, 14143803, 14143826, 14143832, 14143849, 14143855 |
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