This brand name is authorized in Austria, Canada, Estonia, Spain, Finland, France, Croatia, Ireland, Lithuania, Netherlands, Poland, Romania, United Kingdom
The drug ATRIANCE contains one active pharmaceutical ingredient (API):
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1
Nelarabine
UNII 60158CV180 - NELARABINE
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Nelarabine is a pro-drug of the deoxyguanosine analogue ara-G. Accumulation of ara-GTP in leukaemic blasts allows for preferential incorporation of ara-GTP into deoxyribonucleic acid (DNA) leading to inhibition of DNA synthesis. This results in cell death. Other mechanisms may contribute to the cytotoxic effects of nelarabine. In vitro, T-cells are more sensitive than B-cells to the cytotoxic effects of nelarabine. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| ATRIANCE Solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01BB07 | Nelarabine | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BB Purine analogues |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 02299925 |
| Country: EE | Ravimiamet | Identifier(s): 1306763, 1826568, 1849585, 1879702 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 07403001 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 039376, 078365 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 66034512 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 122078, 391314 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1027574, 1088891 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 85030 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100177250 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W64498001, W64498002 |
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