AVANDAMET

This brand name is authorized in Lithuania.

Active ingredients

The drug AVANDAMET contains a combination of these active pharmaceutical ingredients (APIs):

1	Rosiglitazone UNII 05V02F2KDG - ROSIGLITAZONE
	Rosiglitazone is a selective agonist at the PPARγ (peroxisomal proliferator activated receptor gamma) nuclear receptor and is a member of the thiazolidinedione class of anti-diabetic agents. It reduces glycaemia by reducing insulin resistance at adipose tissue, skeletal muscle and liver.
	Read more about Rosiglitazone
2	Metformin UNII 786Z46389E - METFORMIN HYDROCHLORIDE
	Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia.
	Read more about Metformin

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
AVANDAMET Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
A10BD03	Metformin and rosiglitazone	A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BD Combinations of oral blood glucose lowering drugs
Discover more medicines within A10BD03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
LT	Valstybinė vaistų kontrolės tarnyba	1004302, 1004304, 1004306, 1015673, 1015674, 1015675, 1015676, 1015677, 1027589, 1027590, 1027591, 1027592, 1027593, 1027594, 1027595, 1027596, 1027597, 1027598, 1027599, 1027600, 1027601, 1074491