This brand name is authorized in United States. It is also authorized in Australia, Canada, New Zealand.
The drug BREO ELLIPTA contains a combination of these active pharmaceutical ingredients (APIs):
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UNII
JS86977WNV - FLUTICASONE FUROATE
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Fluticasone furoate is a synthetic trifluorinated corticosteroid that possesses a very high affinity for the glucocorticoid receptor and has a potent anti-inflammatory action. |
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40AHO2C6DG - VILANTEROL TRIFENATATE
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Vilanterol is a selective long-acting, beta2-adrenergic agonist (LABA). The pharmacologic effects of beta2-adrenoceptor agonist active substances, including vilanterol, are at least in part attributable to stimulation of intracellular adenylate cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. |
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This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
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| R03AK10 | Vilanterol and fluticasone furoate | R Respiratory system → R03 Drugs for obstructive airway diseases → R03A Adrenergics, inhalants → R03AK Adrenergics and other drugs for obstructive airway diseases |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| AU | Pharmaceutical Benefits Scheme | 11124L, 11129R |
| CA | Health Products and Food Branch | 02408872, 02444186 |
| NZ | Medicines and Medical Devices Safety Authority | 15585, 15586 |
| US | FDA, National Drug Code | 0173-0859, 0173-0882, 70518-2028 |
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