This brand name is authorized in Croatia.
The drug BYOL COMBI contains a combination of these active pharmaceutical ingredients (APIs):
1
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UNII
L35JN3I7SJ - RAMIPRIL
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Ramiprilat, the active metabolite of the prodrug ramipril, inhibits the enzyme dipeptidylcarboxypeptidase I (synonyms: angiotensin-converting enzyme; kininase II). In plasma and tissue this enzyme catalyses the conversion of angiotensin I to the active vasoconstrictor substance angiotensin II, as well as the breakdown of the active vasodilator bradykinin. Reduced angiotensin II formation and inhibition of bradykinin breakdown lead to vasodilatation. |
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2
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UNII
UR59KN573L - BISOPROLOL FUMARATE
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Bisoprolol is a potent highly beta1-selective-adrenoceptor blocking agent, lacking intrinsic stimulating and without relevant membrane stabilising activity. |
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This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| C09BX05 | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09B ACE inhibitors, combinations → C09BX ACE inhibitors, other combinations | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| HR | Agencija za lijekove i medicinske proizvode | HR-H-265900355, HR-H-355894664, HR-H-459290443, HR-H-495084169, HR-H-785874468, HR-H-804824400 |
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