This brand name is authorized in Canada
The drug CALMYLIN ACE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Guaifenesin
UNII 495W7451VQ - GUAIFENESIN
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Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold. |
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2
Codeine
UNII GSL05Y1MN6 - CODEINE PHOSPHATE
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Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
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3
Pheniramine
UNII NYW905655B - PHENIRAMINE MALEATE
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This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R05FA02 | Opium derivatives and expectorants | R Respiratory system → R05 Cough and cold preparations → R05F Cough suppressants and expectorants, combinations → R05FA Opium derivatives and expectorants |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 02198630 |
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