CEFALIUM

This brand name is authorized in Brazil

Active ingredients

The drug CEFALIUM contains a combination of these active pharmaceutical ingredients (APIs):

1 Metoclopramide
UNII 5YNA80E9TO - METOCLOPRAMIDE DIHYDROCHLORIDE

The action of metoclopramide is closely associated with parasympathetic nervous control of the upper gastro-intestinal tract where it has the effect of encouraging normal peristaltic action. This provides for a fundamental approach to the control of those conditions where disturbed gastrointestinal motility is a common underlying factor.

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2 Paracetamol
UNII 362O9ITL9D - ACETAMINOPHEN

Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain.

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3 Dihydroergotamine
UNII 81AXN7R2QT - DIHYDROERGOTAMINE MESYLATE

Dihydroergotamine binds with high affinity to 5-HT1Dα and 5-HT1Dβ receptors. It also binds with high affinity to serotonin 5-HT1A, 5-HT2A, and 5-HT2C receptors. The therapeutic activity of dihydroergotamine in migraine is generally attributed to the agonist effect at 5-HT1D receptors.

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4 Caffeine anhydrous
UNII 3G6A5W338E - CAFFEINE

Caffeine is structurally related to the methylxanthines theophylline and theobromine. Caffeine’s main action is as a CNS stimulant.

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Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 500501901118417

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