CIALIS

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Ireland, Israel, Italy, Japan, Lithuania, Mexico, Nigeria, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States, South Africa

Active ingredients

The drug CIALIS contains one active pharmaceutical ingredient (API):

1 Tadalafil UNII 742SXX0ICT - TADALAFIL

Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection. The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle of the prostate, the bladder and their vascular supply. The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced. Read about Tadalafil

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
CIALIS 2.5 mg Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC
CIALIS 5 mg Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
G04BE08	Tadalafil	G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction
Discover more medicines within G04BE08

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 4596X, 4597Y
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 507600501115212, 507600502111210, 507600503118219, 507600504114217, 507612050017003, 507612090017303
Country: CA	Health Products and Food Branch	Identifier(s): 02248088, 02248089, 02296888, 02296896
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 29240-05-10, 29664-02-11
Country: EE	Ravimiamet	Identifier(s): 1123951, 1123962, 1123973, 1123984, 1213243, 1306976, 1306987, 1306998, 1495492, 1644690
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 02237001, 02237001IP1, 02237003, 02237003IP1, 02237003IP2, 02237003IP3, 02237004, 02237005, 02237008, 02237008IP
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 008927, 008950, 012273, 021256, 063820, 100291, 100300
Country: FR	Base de données publique des médicaments	Identifier(s): 65834394, 65958239, 68937321, 69226514
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 144953, 150013, 150018, 41060, 41064, 41065
Country: HK	Department of Health Drug Office	Identifier(s): 51228, 51229, 60772, 60773
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 4630, 4631, 4633, 6218, 6219
Country: IT	Agenzia del Farmaco	Identifier(s): 035672056
Country: JP	医薬品医療機器総合機構	Identifier(s): 2590016F5026, 2590016F6022, 2590016F7029
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1011136, 1011137, 1011138, 1011139, 1028246, 1028247, 1028248, 1028249, 1052686, 1052687, 1063641, 1065132, 1070287
Country: MX	Comisión Federal para la Protección contra Riesgos Sanitarios	Identifier(s): 181M2002
Country: NG	Registered Drug Product Database	Identifier(s): 04-5196
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 68233, 68241, 86274
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 10307, 10873, 12810, 12811
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100113853, 100113860, 100166890, 100170408
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W12050001, W12051004, W12051005, W12051006, W12051007, W52380001, W52381001, W52381002
Country: SG	Health Sciences Authority	Identifier(s): 12181P, 13631P, 13632P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699673098104, 8699673098111, 8699673098128, 8699673098135, 8699673098142, 8699673098173
Country: US	FDA, National Drug Code	Identifier(s): 0002-4462, 0002-4463, 0002-4464, 0002-4465, 43063-236, 43353-044, 43353-857, 50436-4462, 50436-4463, 50436-4464, 50436-4465, 55154-1832, 63629-4601, 63629-6367, 63629-6769, 63629-7145
Country: ZA	Health Products Regulatory Authority	Identifier(s): 36/7.1.5/0384, 41/7.1.5/0644