CIALIS

This brand name is authorized in United States. It is also authorized in Australia, Austria, Brazil, Canada, Cyprus, Ecuador, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Italy, Japan, Lithuania, Mexico, Netherlands, New Zealand, Nigeria, Poland, Romania, Singapore, South Africa, Spain, Turkey, UK.

Active ingredients

The drug CIALIS contains one active pharmaceutical ingredient (API):

1	Tadalafil UNII 742SXX0ICT - TADALAFIL
	Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). When sexual stimulation causes the local release of nitric oxide, inhibition of PDE5 by tadalafil produces increased levels of cGMP in the corpus cavernosum. This results in smooth muscle relaxation and inflow of blood into the penile tissues, thereby producing an erection. The effect of PDE5 inhibition on cGMP concentration in the corpus cavernosum is also observed in the smooth muscle of the prostate, the bladder and their vascular supply. The resulting vascular relaxation increases blood perfusion which may be the mechanism by which symptoms of benign prostatic hyperplasia are reduced.
	Read more about Tadalafil

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
CIALIS 2.5 mg Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)
CIALIS 5 mg Film-coated tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
G04BE08	Tadalafil	G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction
Discover more medicines within G04BE08

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	4596X, 4597Y
BR	Câmara de Regulação do Mercado de Medicamentos	507600501115212, 507600502111210, 507600503118219, 507600504114217, 507612050017003, 507612090017303
CA	Health Products and Food Branch	02248088, 02248089, 02296888, 02296896
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	29240-05-10, 29664-02-11
EE	Ravimiamet	1123951, 1123962, 1123973, 1123984, 1213243, 1306976, 1306987, 1306998, 1495492, 1644690
ES	Centro de información online de medicamentos de la AEMPS	02237001, 02237001IP1, 02237003, 02237003IP1, 02237003IP2, 02237003IP3, 02237004, 02237005, 02237008, 02237008IP
FI	Lääkealan turvallisuus- ja kehittämiskeskus	008927, 008950, 012273, 021256, 063820, 100291, 100300
FR	Base de données publique des médicaments	65834394, 65958239, 68937321, 69226514
GB	Medicines & Healthcare Products Regulatory Agency	144953, 150013, 150018, 41060, 41064, 41065
HK	Department of Health Drug Office	51228, 51229, 60772, 60773
IL	מִשְׂרַד הַבְּרִיאוּת	4630, 4631, 4633, 6218, 6219
IT	Agenzia del Farmaco	035672056
JP	医薬品医療機器総合機構	2590016F5026, 2590016F6022, 2590016F7029
LT	Valstybinė vaistų kontrolės tarnyba	1011136, 1011137, 1011138, 1011139, 1028246, 1028247, 1028248, 1028249, 1052686, 1052687, 1063641, 1065132, 1070287
MX	Comisión Federal para la Protección contra Riesgos Sanitarios	181M2002
NG	Registered Drug Product Database	04-5196
Switch country to Nigeria in order to find specific presentations of CIALIS
NL	Z-Index G-Standaard, PRK	68233, 68241, 86274
NZ	Medicines and Medical Devices Safety Authority	10307, 10873, 12810, 12811
PL	Rejestru Produktów Leczniczych	100113853, 100113860, 100166890, 100170408
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W12050001, W12051004, W12051005, W12051006, W12051007, W52380001, W52381001, W52381002
SG	Health Sciences Authority	12181P, 13631P, 13632P
TR	İlaç ve Tıbbi Cihaz Kurumu	8699673098104, 8699673098111, 8699673098128, 8699673098135, 8699673098142, 8699673098173
US	FDA, National Drug Code	0002-4462, 0002-4463, 0002-4464, 0002-4465, 43063-236, 43353-044, 43353-857, 50436-4462, 50436-4463, 50436-4464, 50436-4465, 55154-1832, 63629-4601, 63629-6367, 63629-6769, 63629-7145
ZA	Health Products Regulatory Authority	36/7.1.5/0384, 41/7.1.5/0644