This brand name is authorized in Ecuador
The drug CODETOL contains a combination of these active pharmaceutical ingredients (APIs):
|
1
Codeine
UNII GSL05Y1MN6 - CODEINE PHOSPHATE
|
|
Codeine is a centrally acting weak analgesic. Codeine exerts its effect through ฮผ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
|
2
Pseudoephedrine
UNII 6V9V2RYJ8N - PSEUDOEPHEDRINE HYDROCHLORIDE
|
|
Pseudoephedrine is a sympathomimetic agent with direct and indirect effects on adrenergic receptors. It has alpha and beta adrenergic activity and some stimulant effect on the central nervous system. The sympathomimetic effect of pseudoephedrine produces vasoconstriction which in turn relieves nasal congestion. |
|
3
Chlorphenamine
UNII V1Q0O9OJ9Z - CHLORPHENIRAMINE MALEATE
|
|
Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R05DA | Opium alkaloids and derivatives | R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EC | Agencia Nacional de Regulaciรณn, Control y Vigilancia Sanitaria | Identifier(s): 21.583-1-01-04, 21.677-1-11-03 |
ยฉ All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
