This brand name is authorized in Croatia, Poland, Romania
The drug COROSWERA contains a combination of these active pharmaceutical ingredients (APIs):
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1
Rosuvastatin
UNII 83MVU38M7Q - ROSUVASTATIN CALCIUM
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Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles. |
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2
Ezetimibe
UNII EOR26LQQ24 - EZETIMIBE
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Ezetimibe is in a new class of lipid-lowering compounds that selectively inhibit the intestinal absorption of cholesterol. The molecular target of ezetimibe is the sterol transporter, Niemann-Pick C1-Like 1 (NPC1L1), which is responsible for the intestinal uptake of cholesterol. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10BA06 | C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BA Combinations of various lipid modifying agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: HR | Agencija za lijekove i medicinske proizvode | Identifier(s): HR-H-145186580, HR-H-775674698, HR-H-919934131 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100398904, 100398910, 100398927, 100398933, 100398940 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W65531001, W65531002, W65531003, W65531004, W65531005, W65531006, W65531007, W65531008, W65531009, W65535001, W65535002, W65535003, W65535004, W65535005, W65535006, W65535007, W65535008, W65535009, W65536001, W65536002, W65536003, W65536004, W65536005, W65536006, W65536007, W65537001, W65537002, W65537003, W65537004, W65537005, W65537006, W65537007, W65537008, W65537009, W65538001, W65538002, W65538003, W65538004, W65538005, W65538006, W65538007, W65538008, W65538009 |
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