This brand name is authorized in United States. It is also authorized in Austria, Croatia, Estonia, France, Ireland, Italy, Lithuania, Spain, UK.
The drug EBGLYSS contains one active pharmaceutical ingredient (API):
1
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UNII
U9JLP7V031 - LEBRIKIZUMAB
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Lebrikizumab is an immunoglobulin (IgG4) monoclonal antibody that binds with high affinity to interleukin (IL)-13 and selectively inhibits IL-13 signalling through the IL-4 receptor alpha (IL-4Rα)/ IL-13 receptor alpha 1 (IL-13Rα1) heterodimer, thereby inhibiting the downstream effects of IL-13. Inhibition of IL-13 signalling is expected to be of benefit in diseases in which IL-13 is a key contributor to the disease pathogenesis. Lebrikizumab does not prevent the binding of IL-13 to the IL-13 receptor alpha 2 (IL-13Rα2 or decoy receptor), which allows the internalisation of IL-13 into the cell. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| EBGLYSS Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| EE | Ravimiamet | 3055980, 3055991, 3056004, 3056015, 3056026, 3056037, 3056048, 3056059, 3056060, 3056071, 3056082, 3056093 |
| ES | Centro de información online de medicamentos de la AEMPS | 1231765001, 1231765007 |
| FR | Base de données publique des médicaments | 63696560, 65119162 |
| IT | Agenzia del Farmaco | 050964016, 050964028, 050964030, 050964042, 050964079, 050964081, 050964093, 050964105, 050964117, 050964129 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1098146, 1098147, 1098148, 1098149, 1098150, 1098151, 1098152, 1098153, 1098154, 1098155, 1098156, 1098157 |
| US | FDA, National Drug Code | 0002-7772, 0002-7797 |
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