This brand name is authorized in Austria, Estonia, Croatia, Ireland, Italy, Lithuania, United Kingdom, United States
The drug EBGLYSS contains one active pharmaceutical ingredient (API):
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Lebrikizumab
UNII U9JLP7V031 - LEBRIKIZUMAB
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Lebrikizumab is an immunoglobulin (IgG4) monoclonal antibody that binds with high affinity to interleukin (IL)-13 and selectively inhibits IL-13 signalling through the IL-4 receptor alpha (IL-4Rα)/ IL-13 receptor alpha 1 (IL-13Rα1) heterodimer, thereby inhibiting the downstream effects of IL-13. Inhibition of IL-13 signalling is expected to be of benefit in diseases in which IL-13 is a key contributor to the disease pathogenesis. Lebrikizumab does not prevent the binding of IL-13 to the IL-13 receptor alpha 2 (IL-13Rα2 or decoy receptor), which allows the internalisation of IL-13 into the cell. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| EBGLYSS Solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 3055980, 3055991, 3056004, 3056015, 3056026, 3056037, 3056048, 3056059, 3056060, 3056071, 3056082, 3056093 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 050964016, 050964028, 050964030, 050964042, 050964079, 050964081, 050964093, 050964105, 050964117, 050964129 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1098146, 1098147, 1098148, 1098149, 1098150, 1098151, 1098152, 1098153, 1098154, 1098155, 1098156, 1098157 |
| Country: US | FDA, National Drug Code | Identifier(s): 0002-7772, 0002-7797 |
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