ENBREL

This brand name is authorized in Albania, Austria, Australia, Brazil, Canada, Cyprus, Germany, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Tunisia, Turkey, United Kingdom, United States, South Africa

Active ingredients

The drug ENBREL contains one active pharmaceutical ingredient (API):

1 Etanercept UNII OP401G7OJC - ETANERCEPT

Etanercept is a competitive inhibitor of TNF binding to its cell surface receptors, and thereby inhibits the biological activity of TNF. The mechanism of action of etanercept is thought to be its competitive inhibition of TNF binding to cell surface TNFR, preventing TNF-mediated cellular responses by rendering TNF biologically inactive. Read about Etanercept

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ENBREL Powder for solution for injection	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L04AB01	Etanercept	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AB Tumor necrosis factor alpha (TNF-α) inhibitors
Discover more medicines within L04AB01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AL	Fondi i Sigurimit të Detyrueshëm të Kujdesit Shëndetësor	Identifier(s): 663/96
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 11196G, 11197H, 11198J, 11201M, 11204Q, 11207W, 11208X, 11219L, 11220M, 11222P, 11223Q, 11224R, 1954W, 1963H, 1964J, 3445H, 3446J, 3447K, 3448L, 3449M, 3450N, 5733R, 5734T, 5735W, 6367D, 8637N, 8638P, 8778B, 8779C, 9035M, 9036N, 9037P, 9085E, 9086F, 9087G, 9088H, 9089J, 9090K, 9091L, 9429G, 9431J, 9455P, 9456Q, 9457R, 9458T, 9459W, 9460X, 9461Y, 9462B, 9615C, 9641K
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 552817080001717, 552817090002217, 552817090002317, 552817090002417, 552817090002517, 552817090002817, 552817090002917, 552818090064903, 552818090065003, 552818090065103, 552818090065203
Country: CA	Health Products and Food Branch	Identifier(s): 02242903, 02274728
Country: DE	Bundesinstitut für Arzneimittel und Medizinprodukte	Identifier(s): 00021640, 00021657, 00099889, 00121620, 00671912, 00676660, 00762460, 00970879, 01189991, 01440327, 02199425, 02199431, 02239159, 02241067, 02241073, 02241096, 02241104, 02241110, 02291510, 02847427, 02953365, 03004292, 03323844, 03752953, 03753289, 03753295, 03864267, 04227108, 04422407, 04425423, 04426055, 04427132, 04428367, 04446342, 04446359, 04492419, 04492425, 04537317, 04780302, 04973490, 04977039, 05541309, 05958481, 05958498, 06057047, 06093020, 06129344, 06129350, 06142741, 06152685, 06161916, 06161922, 06407671, 06452938, 06452944, 06497668, 06680059, 06934554, 06934560, 07753435, 07753441, 08929617, 09008233, 09008256, 09236218, 09334518, 09392906, 09521309, 09635585, 09635591, 09635616, 09637348, 09640439, 09640474, 09708781, 09782636, 09782642, 09893985, 10079623, 10221009, 10399380, 10709082, 10709099, 10709107, 10709113, 10786243, 10786266, 10813299, 10933000, 10933017, 11479282, 12521709, 12521721, 12521738, 12571357, 12571363, 13243767, 13243773, 13243796, 13243804, 13246493, 13246530, 13785965, 14139919, 14139931, 14139948, 14227138, 14227428, 14327986, 14328000, 14328017, 15235944, 15235967, 15609161, 15609178, 15612720, 16165921, 16680468, 16680474, 16743973, 16744010, 16754847, 16909534, 16913211, 17147635
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 109-MBE-0817, 140-MBE-0619
Country: EE	Ravimiamet	Identifier(s): 1011665, 1209608, 1209619, 1209620, 1209631, 1209642, 1209653, 1209664, 1209675, 1213333, 1265600, 1265611, 1265622, 1265633, 1265644, 1265655, 1460180, 1460191, 1460203, 1538704, 1762253, 1762264, 1762275, 1777811
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 199126023, 99126003, 99126013, 99126017, 99126020, 99126022
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 047042, 047560, 065778, 416609, 487692, 566661
Country: FR	Base de données publique des médicaments	Identifier(s): 61187835, 63886766, 64959320, 66393935, 68667580, 68672848
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 109678, 110336, 159804, 199215, 348341, 41567
Country: HK	Department of Health Drug Office	Identifier(s): 48914, 55983, 55984, 59796
Country: IE	Health Products Regulatory Authority	Identifier(s): 88039, 88095, 88098, 88099, 88245, 88246, 88863
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 4638, 7335, 7549, 7550
Country: JP	医薬品医療機器総合機構	Identifier(s): 3999424D1029, 3999424D2025, 3999424G1025, 3999424G2021, 3999424G3028, 3999424G4024, 3999424G5020, 3999424G6027
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1027990, 1027991, 1027992, 1027993, 1027994, 1027995, 1027996, 1027998, 1027999, 1028000, 1028001, 1028002, 1028003, 1028004, 1061303, 1076376, 1076377, 1076378, 1084548, 1084549, 1085078, 1085079, 1085080, 1085944
Country: NL	Z-Index G-Standaard	Identifier(s): 15208826, 15208850, 15448037
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 148032, 66125, 81647, 81655
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 12348, 12349, 8765
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100211923, 100226362, 100226379, 100226385, 100226416, 100250886, 100417530
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W64809001, W64810001, W64811002, W64812002
Country: SG	Health Sciences Authority	Identifier(s): 11854P, 13834P, 13835P, 14440P
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 8013111H, 8013112H
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8681308277435, 8681308955043, 8681308955050, 8681308955555, 8681308958600, 8681308959133, 8681308959140
Country: US	FDA, National Drug Code	Identifier(s): 50090-4490, 58406-010, 58406-021, 58406-032, 58406-044, 58406-055, 58406-435, 58406-445, 58406-446, 58406-455, 58406-456
Country: ZA	Health Products Regulatory Authority	Identifier(s): 34/3.1/0330, 41/3.1/0762, 41/3.1/0763