ENZYPLEX

This brand name is authorized in Hong Kong SAR China, Singapore.

Active ingredients

The drug ENZYPLEX contains a combination of these active pharmaceutical ingredients (APIs):

1
Amylase
2
UNII 568ET80C3D - CALCIUM PANTOTHENATE
 

Pantothenic acid is incorporated into co-enzyme A and is involved in metabolic pathways involving acetylation which includes detoxification of drug molecules and biosynthesis of cholesterol, steroid hormones, mucopolysaccharides and acetylcholine. CoA has an essential function in lipid metabolism.

 
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3
Lipase
UNII 8MYC33932O - PANCRELIPASE LIPASE
4
UNII 25X51I8RD4 - NIACINAMIDE
 

Niacin (nicotinic acid) is an essential B complex Vitamin (B3), whose deficiency results in the clinical syndrome known as pellagra. Nicotinamide (niacinamide), the active ingredient, is the physiologically active form of niacin and is the chemical form of Vitamin B3 found in virtually all multivitamin products. Though nicotinic acid and nicotinamide are so closely related chemically, they differ somewhat in pharmacological properties.

 
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5
UNII 92RU3N3Y1O - DIMETHICONE
 

Dimeticone is used in many pharmaceutical and cosmetic preparations. A 4% concentration has been found to affect the physico-physiological activity of lice.

 
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6
 

Protease is an trypsin that catalyzes (increases the rate of) proteolysis, the breakdown of proteins into smaller polypeptides or single amino acids. They do this by cleaving the peptide bonds within proteins by hydrolysis, a reaction where water breaks bonds.

 
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7
UNII X66NSO3N35 - THIAMINE
 

Thiamine pyrophosphate (TPP), the coenzymatic form of thiamine, is involved in two main types of metabolic reactions: decarboxylation of α-ketoacids (e.g. pyruvate, α-ketoglutarate and branched-chain keto acids) and transketolation (e.g. among hexose and pentose phosphates). Therefore, the principal physiological role of thiamine is as a coenzyme in carbohydrate metabolism, where TPP is required for several stages in the breakdown of glucose to provide energy.

 
Read more about Vitamin B1
8
UNII TLM2976OFR - RIBOFLAVIN
 

Riboflavine is phosphorylated to flavine mononucleotide and flavine adenine dinucleotide which act as co-enzymes in the respiratory chain and in oxidative phosphorylation. Riboflavine deficiency presents with ocular symptoms, as well as lesions on the lips and at angles of the mouth.

 
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9
UNII KV2JZ1BI6Z - PYRIDOXINE
 

Pyridoxine hydrochloride is Vitamin B6. It is converted to pyridoxal phosphate which is the co-enzyme for a variety of metabolic transformations. It is essential for human nutrition.

 
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10
UNII P6YC3EG204 - CYANOCOBALAMIN
 

Hydroxocobalamin is used in the treatment and prevention of Vitamin B12 deficiency. For adults, the daily requirement of Vitamin B12 is probably about 1 to 2 micrograms and this amount is present in most normal diets. However, Vitamin B12 only occurs in animal products, not in vegetables, and therefore strict vegetarian or vegan diets that exclude dairy products may provide an inadequate amount, although a deficiency may not be apparent for many years.

 
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11
UNII 005990WHZZ - DEOXYCHOLIC ACID
 

Deoxycholic acid is a cytolytic drug, which when injected into localized subcutaneous fat, physically disrupts the cell membrane of adipocytes. The destruction of adipocytes elicits a tissue response in which macrophages are attracted to the area to eliminate cellular debris and lipids, which are then cleared through natural processes.

 
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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
A09AA02 Multienzymes (lipase, protease etc.) A Alimentary tract and metabolism → A09 Digestives, incl. enzymes → A09A Digestives, incl. enzymes → A09AA Diastase
Discover more medicines within A09AA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
HK Department of Health Drug Office 06544
SG Health Sciences Authority 06211P

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