ERIVEDGE

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Lithuania, Netherlands, New Zealand, Poland, Romania, Turkey, United Kingdom, United States, South Africa

Active ingredients

The drug ERIVEDGE contains one active pharmaceutical ingredient (API):

1 Vismodegib UNII 25X868M3DS - VISMODEGIB

Vismodegib is an orally available small-molecule inhibitor of the Hedgehog pathway. Hedgehog pathway signalling through the Smoothened transmembrane protein (SMO) leads to the activation and nuclear localisation of Glioma-Associated Oncogene (GLI) transcription factors and induction of Hedgehog target genes. Vismodegib binds to and inhibits the SMO protein thereby blocking Hedgehog signal transduction. Read about Vismodegib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ERIVEDGE Hard capsule	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01XJ01		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XJ Hedgehog pathway inhibitors
Discover more medicines within L01XJ01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 11070P
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 529217010026901
Country: CA	Health Products and Food Branch	Identifier(s): 02409267
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 365460513
Country: EE	Ravimiamet	Identifier(s): 1621505
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 113848001
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 376974
Country: FR	Base de données publique des médicaments	Identifier(s): 67507605
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 227643
Country: HK	Department of Health Drug Office	Identifier(s): 63786
Country: IE	Health Products Regulatory Authority	Identifier(s): 88868
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 7166
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1070868
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 106585
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 15947
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100299668
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W64376001
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699505152066
Country: US	FDA, National Drug Code	Identifier(s): 50242-140
Country: ZA	Health Products Regulatory Authority	Identifier(s): 48/32.16/0658