This brand name is authorized in South Africa
The drug GENCIT SIMPLEX contains a combination of these active pharmaceutical ingredients (APIs):
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1
Citric acid
UNII 2968PHW8QP - CITRIC ACID MONOHYDRATE
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Potassium citrate is indicated for the management of renal tubular acidosis with calcium stones, hypocitraturic calcium oxalate nephrolithiasis of any etiology, uric acid lithiasis with or without calcium stones. When potassium citrate is given orally, the metabolism of absorbed citrate produces an alkaline load. The induced alkaline load in turn increases urinary pH and raises urinary citrate by augmenting citrate clearance without measurably altering ultrafilterable serum citrate. Thus, potassium citrate therapy appears to increase urinary citrate principally by modifying the renal handling of citrate, rather than by increasing the filtered load of citrate. |
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2
Potassium citrate
UNII EE90ONI6FF - POTASSIUM CITRATE
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Citrate and citric acid solutions are systematic and urinary alkalinizers thereby providing symptomatic relief of dysuria. |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: ZA | Health Products Regulatory Authority | Identifier(s): H/18.3/1913 |
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