GLIOLAN

This brand name is authorized in Austria, Cyprus, Estonia, Finland, France, Hong Kong SAR China, Ireland, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Spain, UK.

Active ingredients

The drug GLIOLAN contains one active pharmaceutical ingredient (API):

1
UNII V35KBM8JGR - AMINOLEVULINIC ACID HYDROCHLORIDE
 

5-Aminolevulinic acid (5-ALA) is a natural biochemical precursor of heme that is metabolised in a series of enzymatic reactions to fluorescent porphyrins, particularly PPIX. 5-ALA synthesis is regulated by an intracellular pool of free heme via a negative feedback mechanism. Administration of excess exogenous 5-ALA avoids the negative feedback control, and accumulation of PPIX occurs in target tissue. In the presence of visible light, fluorescence of PPIX (photodynamic effect) in certain target tissues can be used for photodynamic diagnosis.

 
Read more about Aminolevulinic acid

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 Gliolan 30mg/ml powder for oral solution MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 GLIOLAN Powder for oral solution MPI, EU: SmPC European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
L01XD04 Aminolevulinic acid L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XD Sensitizers used in photodynamic/radiation therapy
Discover more medicines within L01XD04

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
EE Ravimiamet 1347184, 1347195, 1347207
ES Centro de información online de medicamentos de la AEMPS 07413001
FI Lääkealan turvallisuus- ja kehittämiskeskus 026045
FR Base de données publique des médicaments 63389433
GB Medicines & Healthcare Products Regulatory Agency 198663
HK Department of Health Drug Office 62756
IT Agenzia del Farmaco 046649012, 046649024, 046649036
LT Valstybinė vaistų kontrolės tarnyba 1028660, 1028661, 1028662
NL Z-Index G-Standaard, PRK 95826
NZ Medicines and Medical Devices Safety Authority 17280
PL Rejestru Produktów Leczniczych 100021358
RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale W69482001, W69482002, W69482003
SG Health Sciences Authority 15244P

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.