GLIOLAN

This brand name is authorized in Austria, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Ireland, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, United Kingdom

Active ingredients

The drug GLIOLAN contains one active pharmaceutical ingredient (API):

1 Aminolevulinic acid
UNII V35KBM8JGR - AMINOLEVULINIC ACID HYDROCHLORIDE

5-Aminolevulinic acid (5-ALA) is a natural biochemical precursor of heme that is metabolised in a series of enzymatic reactions to fluorescent porphyrins, particularly PPIX. 5-ALA synthesis is regulated by an intracellular pool of free heme via a negative feedback mechanism. Administration of excess exogenous 5-ALA avoids the negative feedback control, and accumulation of PPIX occurs in target tissue. In the presence of visible light, fluorescence of PPIX (photodynamic effect) in certain target tissues can be used for photodynamic diagnosis.

Read about Aminolevulinic acid

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
GLIOLAN Powder for oral solution European Medicines Agency (EU) MPI, EU: SmPC
Gliolan 30mg/ml powder for oral solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
L01XD04 Aminolevulinic acid L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XD Sensitizers used in photodynamic/radiation therapy
Discover more medicines within L01XD04

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EE Ravimiamet Identifier(s): 1347184, 1347195, 1347207
Country: ES Centro de información online de medicamentos de la AEMPS Identifier(s): 07413001
Country: FI Lääkealan turvallisuus- ja kehittämiskeskus Identifier(s): 026045
Country: FR Base de données publique des médicaments Identifier(s): 63389433
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 198663
Country: HK Department of Health Drug Office Identifier(s): 62756
Country: IT Agenzia del Farmaco Identifier(s): 046649012, 046649024, 046649036
Country: LT Valstybinė vaistų kontrolės tarnyba Identifier(s): 1028660, 1028661, 1028662
Country: NL Z-Index G-Standaard, PRK Identifier(s): 95826
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 17280
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100021358
Country: RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale Identifier(s): W69482001, W69482002, W69482003
Country: SG Health Sciences Authority Identifier(s): 15244P

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.