This brand name is authorized in Austria, Brazil, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Ireland, Israel, Japan, Lithuania, Netherlands, Poland, Romania, Singapore, United Kingdom, United States
The drug HEPSERA contains one active pharmaceutical ingredient (API):
1
Adefovir dipivoxil
UNII U6Q8Z01514 - ADEFOVIR DIPIVOXIL
|
Adefovir dipivoxil is an oral prodrug of adefovir, an acyclic nucleotide phosphonate analogue of adenosine monophosphate, which is actively transported into mammalian cells where it is converted by host enzymes to adefovir diphosphate. Adefovir diphosphate inhibits viral polymerases by competing for direct binding with the natural substrate (deoxyadenosine triphosphate) and, after incorporation into viral DNA, causes DNA chain termination. |
Below package inserts are available for further reading:
Title | Information Source | Document Type | |
---|---|---|---|
Hepsera 10 mg tablets | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
HEPSERA Tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
J05AF08 | Adefovir dipivoxil | J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AF Nucleoside and nucleotide reverse transcriptase inhibitors |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 510610001115217 |
Country: CA | Health Products and Food Branch | Identifier(s): 02247823 |
Country: EE | Ravimiamet | Identifier(s): 1203073, 1295760 |
Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 03251001 |
Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 014510 |
Country: FR | Base de données publique des médicaments | Identifier(s): 60954219 |
Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 78426 |
Country: HK | Department of Health Drug Office | Identifier(s): 65358 |
Country: IE | Health Products Regulatory Authority | Identifier(s): 88503 |
Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 4714 |
Country: JP | 医薬品医療機器総合機構 | Identifier(s): 6250026F1020 |
Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1028725, 1028726, 1075653 |
Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 70629 |
Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100127602 |
Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W64757001, W64757002 |
Country: SG | Health Sciences Authority | Identifier(s): 12341P |
Country: US | FDA, National Drug Code | Identifier(s): 61958-0501 |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.