This brand name is authorized in Lithuania, United States
The drug HYMPAVZI contains one active pharmaceutical ingredient (API):
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Marstacimab
UNII 0UB3OA67O7 - MARSTACIMAB
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Marstacimab is a human monoclonal IgG1 antibody directed against the Kunitz domain 2 (K2) of tissue factor pathway inhibitor (TFPI), the primary inhibitor of the extrinsic coagulation cascade. TFPI initially binds to and inhibits the factor Xa active site via its second Kunitz inhibitor domain (K2). The action of marstacimab to neutralise the inhibitory activity of TFPI may serve to enhance the extrinsic pathway and bypass deficiencies in the intrinsic pathway of coagulation by increasing free factor Xa available to increase thrombin generation and promote haemostasis. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| HYMPAVZI Solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1101989, 1101990 |
| Country: US | FDA, National Drug Code | Identifier(s): 0069-1510, 0069-2151 |
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