IFEX

This brand name is authorized in Canada, United States

Active ingredients

The drug IFEX contains one active pharmaceutical ingredient (API):

1 Ifosfamide UNII UM20QQM95Y - IFOSFAMIDE

Ifosfamide is an antineoplastic, a cytotoxic alkylating agent. It is a prodrug and shows no in vitro cytotoxic activity until activated by microsomal enzymes. The cytotoxic activity of ifosfamide (alkylation of the nucleophilic centres in the cells) is associated with the activated oxazaphosphorine ring hydroxylated at the C4 atom which interacts with DNA-DNA cross linking. This activity manifests itself by blocking the late S and early G2 phases of the cell cycle. Read about Ifosfamide

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
IFEX Powder for solution for injection	FDA, National Drug Code (US)	MPI, US: SPL/PLR

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01AA06	Ifosfamide	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AA Nitrogen mustard analogues
Discover more medicines within L01AA06

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: CA	Health Products and Food Branch	Identifier(s): 02241356, 02241357
Country: US	FDA, National Drug Code	Identifier(s): 0338-3991, 0338-3993