This brand name is authorized in Canada, United States
The drug INVOKAMET contains a combination of these active pharmaceutical ingredients (APIs):
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1
Canagliflozin
UNII 0SAC974Z85 - CANAGLIFLOZIN
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Canagliflozin is an orally-active inhibitor of SGLT2. The SGLT2 transporter, expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. By inhibiting SGLT2, canagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose (RTG). |
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2
Metformin
UNII 786Z46389E - METFORMIN HYDROCHLORIDE
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Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A10BD16 | Metformin and canagliflozin | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BD Combinations of oral blood glucose lowering drugs |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 02455404, 02455420, 02455439, 02455455 |
| Country: US | FDA, National Drug Code | Identifier(s): 50458-540, 50458-541, 50458-542, 50458-543, 50458-940, 50458-941, 50458-942, 50458-943 |
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