JUXTAPID

This brand name is authorized in United States. It is also authorized in Canada, Japan.

Active ingredients

The drug JUXTAPID contains one active pharmaceutical ingredient (API):

1
UNII X4S83CP54E - LOMITAPIDE MESYLATE
 

Lomitapide is a selective inhibitor of microsomal transfer protein (MTP), an intracellular lipid-transfer protein that is found in the lumen of the endoplasmic reticulum and is responsible for binding and shuttling individual lipid molecules between membranes. MTP plays a key role in the assembly of apo B containing lipoproteins in the liver and intestines. Inhibition of MTP reduces lipoprotein secretion and circulating concentrations of lipoprotein-borne lipids including cholesterol and triglycerides.

 
Read more about Lomitapide

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 JUXTAPID Capsule MPI, US: SPL/PLR FDA, National Drug Code (US)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
C10AX12 C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AX Other lipid modifying agents
Discover more medicines within C10AX12

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
CA Health Products and Food Branch 02420341, 02420376, 02420384
JP 医薬品医療機器総合機構 2189020M1023, 2189020M2020, 2189020M3026
US FDA, National Drug Code 76431-105, 76431-110, 76431-120, 76431-130

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