This brand name is authorized in Nigeria
The drug KACHAM contains a combination of these active pharmaceutical ingredients (APIs):
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1
Diclofenac
UNII QTG126297Q - DICLOFENAC SODIUM
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Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms. |
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2
Paracetamol
UNII 362O9ITL9D - ACETAMINOPHEN
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Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain. |
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3
Chlorzoxazone
UNII H0DE420U8G - CHLORZOXAZONE
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Chlorzoxazone is a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex arcs involved in producing and maintaining skeletal muscle spasm of varied etiology. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M03BB53 | Chlorzoxazone, combinations excl. psycholeptics | M Musculo-skeletal system → M03 Muscle relaxants → M03B Muscle relaxants, centrally acting agents → M03BB Oxazol, thiazine, and triazine derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: NG | Registered Drug Product Database | Identifier(s): A4-0486 |
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