This brand name is authorized in France
The drug KANOKAD contains a combination of these active pharmaceutical ingredients (APIs):
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1
Thrombin
UNII 8FB1K07F16 - PROTHROMBIN
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2
Coagulation factor VII
UNII 4156XVB4QD - COAGULATION FACTOR VII HUMAN
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3
Coagulation factor IX
UNII 6U90Y1795T - COAGULATION FACTOR IX HUMAN
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Factor IX is a single chain glycoprotein with a molecular mass of about 68,000 Dalton. It is a vitamin-K dependent coagulation factor and it is synthesised in the liver. Factor IX is activated by factor XIa in the intrinsic coagulation pathway and by the factor VII/tissue factor complex in the extrinsic pathway. Activated factor IX, in combination with activated factor VIII, activates factor X. |
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4
Coagulation factor X
UNII 0P94UQE6SY - COAGULATION FACTOR X HUMAN
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Coagulation factor X is derived from human plasma and used as a replacement for the naturally existing coagulation factor X in patients with hereditary factor X deficiency. |
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5
Protein S
UNII 90J3F6N5FN - PROTEIN S HUMAN
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6
Protein C
UNII 3Z6S89TXPW - PROTEIN C
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Protein C is a serine protease with potent anticoagulant effects, especially in the presence of its cofactor protein S. Protein C exerts its effect by the inactivation of the activated forms of factors V and VIII which leads to a decrease in thrombin formation. Protein C has also been shown to have profibrinolytic effects. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
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| B02BD01 | Coagulation factor IX, II, VII and X in combination | B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BD Blood coagulation factors |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
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| Country: FR | Base de données publique des médicaments | Identifier(s): 69321040 |
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