This brand name is authorized in United States. It is also authorized in Australia, Brazil, Canada, Estonia, Finland, Hong Kong SAR China, Ireland, Israel, Lithuania, Malta, Mexico, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey.
The drug LEUKERAN contains one active pharmaceutical ingredient (API):
1
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UNII
18D0SL7309 - CHLORAMBUCIL
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Chlorambucil is an aromatic nitrogen mustard derivative which acts as a bifunctional alkylating agent. In addition to interference with DNA replication, chlorambucil induces cellular apoptosis via the accumulation of cytosolic p53 and subsequent activation of an apoptosis promoter. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| LEUKERAN Tablets | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| L01AA02 | Chlorambucil | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AA Nitrogen mustard analogues |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| AU | Pharmaceutical Benefits Scheme | 1163F |
| BR | Câmara de Regulação do Mercado de Medicamentos | 505617060041717 |
| CA | Health Products and Food Branch | 00004626 |
| EE | Ravimiamet | 1007345 |
| FI | Lääkealan turvallisuus- ja kehittämiskeskus | 378501 |
| HK | Department of Health Drug Office | 03789 |
| IE | Health Products Regulatory Authority | 31461 |
| IL | מִשְׂרַד הַבְּרִיאוּת | 1112 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1002234, 1069682 |
| MT | Medicines Authority | MA955/00301 |
| MX | Comisión Federal para la Protección contra Riesgos Sanitarios | 50481 |
| NL | Z-Index G-Standaard, PRK | 1694 |
| NZ | Medicines and Medical Devices Safety Authority | 2376 |
| PL | Rejestru Produktów Leczniczych | 100194811, 100330450, 100454307 |
| RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | W58866002 |
| SG | Health Sciences Authority | 11696P |
| TR | İlaç ve Tıbbi Cihaz Kurumu | 8699874080038 |
| US | FDA, National Drug Code | 76388-635 |
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