LOJUXTA

This brand name is authorized in Austria, Brazil, Estonia, France, Croatia, Ireland, Israel, Italy, Lithuania, Netherlands, Poland, Romania, United Kingdom

Active ingredients

The drug LOJUXTA contains one active pharmaceutical ingredient (API):

1 Lomitapide UNII X4S83CP54E - LOMITAPIDE MESYLATE

Lomitapide directly binds and inhibits microsomal triglyceride transfer protein (MTP), which resides in the lumen of the endoplasmic reticulum, thereby preventing the assembly of apo B-containing lipoproteins in enterocytes and hepatocytes. This inhibits the synthesis of chylomicrons and VLDL. The inhibition of the synthesis of VLDL leads to reduced levels of plasma LDL-C. Read about Lomitapide

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
LOJUXTA Hard, capsule	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
C10AX12		C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AX Other lipid modifying agents
Discover more medicines within C10AX12

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 574421050000102, 574421050000202, 574421050000302
Country: EE	Ravimiamet	Identifier(s): 1621707, 1621729, 1621730, 1713484, 1713495, 1713507
Country: FR	Base de données publique des médicaments	Identifier(s): 69243759, 69565055, 69851117
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 234945, 234952, 234963
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 8958, 8959, 8960
Country: IT	Agenzia del Farmaco	Identifier(s): 042920013, 042920025, 042920037, 042920049, 042920052, 042920064
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1071079, 1071080, 1071081, 1080464, 1080465, 1080466
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 106984, 106992, 107018
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100311607, 100311613, 100311620, 100388082, 100388099, 100388107
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W66217001, W66218001, W66219001