This brand name is authorized in Austria, Estonia, Finland, France, Croatia, Ireland, Israel, Italy, Lithuania, Poland, Romania, United Kingdom
The drug LUMYKRAS contains one active pharmaceutical ingredient (API):
|
1
Sotorasib
UNII 2B2VM6UC8G - SOTORASIB
|
|
Sotorasib is a selective KRAS G12C (Kirsten rat sarcoma viral oncogene homolog) inhibitor, which covalently and irreversibly binds to the unique cysteine of KRAS G12C. Inactivation of KRAS G12C by sotorasib blocks tumour cell signalling and survival, inhibits cell growth, and promotes apoptosis selectively in tumours harbouring KRAS G12C, an oncogenic driver of tumourigenesis. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| LUMYKRAS Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01XX73 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1873212, 1873223, 1873234 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 421007 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 63966283 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 9221 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 049858018, 049858020, 049858032 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1093934, 1093935, 1093936 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100462468 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W69079001, W69079002, W69079003 |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
