MADOPAR

This brand name is authorized in Australia, Austria, Croatia, Estonia, Finland, Germany, Hong Kong SAR China, Ireland, Italy, Japan, Lithuania, Malta, Mexico, Netherlands, New Zealand, Poland, Romania, Singapore, South Africa, Spain, Turkey, UK.

Active ingredients

The drug MADOPAR contains a combination of these active pharmaceutical ingredients (APIs):

1	Levodopa UNII 46627O600J - LEVODOPA
	According to the current understanding, the symptoms of Parkinson’s disease are related to depletion of dopamine in the corpus striatum. Dopamine does not cross the blood-brain barrier. Levodopa, the precursor of dopamine, crosses the blood brain barrier and relieves the symptoms of the disease.
	Read more about Levodopa
2	Benserazide UNII B66E5RK36Q - BENSERAZIDE HYDROCHLORIDE
	Benserazide (also called Serazide or Ro 4-4602) is a peripherally acting aromatic L-amino acid decarboxylase or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier.
	Read more about Benserazide

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
MADOPAR Capsule, Rapid dispersible tablet	MPI, EU: SmPC	Medicines and Medical Devices Safety Authority (NZ)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
N04BA02	Levodopa and decarboxylase inhibitor	N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BA Dopa and dopa derivatives
Discover more medicines within N04BA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	2225D, 2226E, 2227F, 2228G, 2229H, 2231K, 8218M, 8219N
DE	Bundesinstitut für Arzneimittel und Medizinprodukte	00125440, 00125457, 00257905, 00257911, 00308956, 00326500, 00326552, 00326569, 01214192, 01351581, 01351612, 01364862, 01364879, 01393622, 01416027, 01602095, 02457212, 02457229, 02535113, 02535136, 03108407, 03108413, 03108436, 03146402, 03146419, 03395789, 03395803, 03501866, 03888606, 03888629, 04471392, 04611611, 04759756, 04759779, 04774796, 04775525, 04800252, 04800269, 04958697, 04958912, 05541976, 05960785, 06865215, 07309189, 07729394, 08699761, 08699784, 09194112, 09194141, 09396732, 12539313
EE	Ravimiamet	1002014, 1077049, 1082911, 1082922, 1085161, 1149544, 1599611, 1599622
ES	Centro de información online de medicamentos de la AEMPS	52146, 62162
FI	Lääkealan turvallisuus- ja kehittämiskeskus	032870, 032888, 372151, 526368
GB	Medicines & Healthcare Products Regulatory Agency	144773, 162060, 175693, 175799, 23992, 23999, 24003, 24012, 24019, 24025
HK	Department of Health Drug Office	15442, 30945, 43315
HR	Agencija za lijekove i medicinske proizvode	HR-H-771762650
IE	Health Products Regulatory Authority	39748, 39756, 61646
IT	Agenzia del Farmaco	023142033
JP	医薬品医療機器総合機構	1169100F1079
LT	Valstybinė vaistų kontrolės tarnyba	1001211, 1001213, 1001215, 1003373
MT	Medicines Authority	AA1343/01301, AA565/40302, AA565/40303, AA565/40304, AA729/00502, AA729/00503
MX	Comisión Federal para la Protección contra Riesgos Sanitarios	82544
NL	Z-Index G-Standaard, PRK	116971, 38563, 56677, 56685, 73695
NZ	Medicines and Medical Devices Safety Authority	1954, 1955, 1956, 1959, 1960
PL	Rejestru Produktów Leczniczych	100040373, 100040404, 100040410, 100040427, 100079040, 100079056, 100193800
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W51325001, W51325002, W58811002
SG	Health Sciences Authority	05195P, 06119P, 06121P, 11075P
TR	İlaç ve Tıbbi Cihaz Kurumu	8699525094841, 8699525094858, 8699525150059, 8699525154828
ZA	Health Products Regulatory Authority	31/5.4.1/0194, P/5.4.1/150