This brand name is authorized in Japan
The drug MEXITIL contains one active pharmaceutical ingredient (API):
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1
Mexiletine
UNII 1U511HHV4Z - MEXILETINE
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Mexiletine blocks sodium channels with a stronger potency in situations of excessive burst of action potentials (use-dependent block) and/or prolonged depolarization (voltage-dependent block), as occurring in diseased tissues, rather than on physiological excitability (resting or tonic block). Mexiletine is, therefore, mostly active on muscle fibres subject to repeated discharges (such as skeletal muscles). It improves myotonic symptoms by decreasing muscle stiffness through reduction of the delay of muscle relaxation. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01BB02 | Mexiletine | C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BB Antiarrhythmics, class Ib |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: JP | 医薬品医療機器総合機構 | Identifier(s): 2129003M1021, 2129003M2028, 2129403A1044 |
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