This brand name is authorized in Ireland, Israel, Malta, United Kingdom
The drug MIGRALEVE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Paracetamol
UNII 362O9ITL9D - ACETAMINOPHEN
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Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain. |
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2
Codeine
UNII GSL05Y1MN6 - CODEINE PHOSPHATE
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Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
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3
Buclizine
UNII 58FQD093NU - BUCLIZINE HYDROCHLORIDE
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Buclizine is a piperazine derivative with the actions and uses of H1-receptor antagonists. It has anti-muscarinic and central sedative properties. The drug is used mainly for its antiemetic action, particularly in the prevention of motion sickness, and in the treatment of migraine in combination with analgesics. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N02AJ09 | N Nervous system → N02 Analgesics → N02A Opioids → N02AJ Opioids in combination with non-opioid analgesics | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 33637, 33639, 33640 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 4287 |
| Country: MT | Medicines Authority | Identifier(s): MA1315/00501 |
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