This brand name is authorized in Austria, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, United Kingdom
The drug MODIGRAF contains one active pharmaceutical ingredient (API):
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1
Tacrolimus
UNII WM0HAQ4WNM - TACROLIMUS
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Tacrolimus is a highly potent immunosuppressive agent. In particular, tacrolimus inhibits the formation of cytotoxic lymphocytes, which are mainly responsible for graft rejection. Tacrolimus suppresses T-cell activation and T-helper-cell dependent B-cell proliferation, as well as the formation of lymphokines (such as interleukins-2, -3, and γ-interferon) and the expression of the interleukin-2 receptor. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| MODIGRAF Granules for oral suspension | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L04AD02 | Tacrolimus | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AD Calcineurin inhibitors |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1422481, 1422504 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 09523001, 09523002 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 059882, 059938 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 61092077, 69208135 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 166585, 166589 |
| Country: IE | Health Products Regulatory Authority | Identifier(s): 88504, 88505 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 040115014, 040115026 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1038370, 1038371 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 104698 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100222795, 100222803 |
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