This brand name is authorized in Austria, Australia, Brazil, France
The drug MUPHORAN contains one active pharmaceutical ingredient (API):
1
Fotemustine
UNII GQ7JL9P5I2 - FOTEMUSTINE
|
Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
L01AD05 | Fotemustine | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AD Nitrosoureas |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 4437M, 7245H |
Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 531300901153318 |
Country: FR | Base de données publique des médicaments | Identifier(s): 63675185 |
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