NEXAVAR

This brand name is authorized in Austria, Australia, Brazil, Canada, Cyprus, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Mexico, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States, South Africa

Active ingredients

The drug NEXAVAR contains one active pharmaceutical ingredient (API):

1 Sorafenib UNII 5T62Q3B36J - SORAFENIB TOSYLATE

Sorafenib is a multikinase inhibitor which has demonstrated both anti-proliferative and anti-angiogenic properties in vitro and in vivo. Sorafenib inhibits the activity of targets present in the tumour cell (CRAF, BRAF, V600E BRAF, c-KIT, and FLT-3) and in the tumour vasculature (CRAF, VEGFR-2, VEGFR-3, and PDGFR-β). Read about Sorafenib

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
NEXAVAR Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01EX02	Sorafenib	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EX Other protein kinase inhibitors
Discover more medicines within L01EX02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 10226F, 10242C, 9380Q
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 538912050012113
Country: CA	Health Products and Food Branch	Identifier(s): 02284227
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 29779-05-11
Country: EE	Ravimiamet	Identifier(s): 1249938
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 06342001, 06342001IP
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 163494
Country: FR	Base de données publique des médicaments	Identifier(s): 64463662
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 106852, 392454
Country: HK	Department of Health Drug Office	Identifier(s): 55409
Country: IE	Health Products Regulatory Authority	Identifier(s): 88133, 89012
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 6135
Country: IT	Agenzia del Farmaco	Identifier(s): 037154010
Country: JP	医薬品医療機器総合機構	Identifier(s): 4291017F1025
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1029584, 1090758
Country: MX	Comisión Federal para la Protección contra Riesgos Sanitarios	Identifier(s): 082M2006
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 81450
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 12471
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100134312
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W63886001
Country: SG	Health Sciences Authority	Identifier(s): 13339P
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699546090044
Country: US	FDA, National Drug Code	Identifier(s): 50419-488
Country: ZA	Health Products Regulatory Authority	Identifier(s): A40/26/0776