This brand name is authorized in Austria, Estonia, Spain, France, Croatia, Ireland, Italy, Lithuania, Poland, Turkey, United Kingdom
The drug NILEMDO contains one active pharmaceutical ingredient (API):
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1
Bempedoic acid
UNII 1EJ6Z6Q368 - BEMPEDOIC ACID
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Bempedoic acid is an adenosine triphosphate citrate lyase (ACL) inhibitor that lowers low-density lipoprotein cholesterol (LDL-C) by inhibition of cholesterol synthesis in the liver. Bempedoic acid requires coenzyme A (CoA) activation by very long-chain acyl-CoA synthetase 1 (ACSVL1) to ETC-1002-CoA. Inhibition of ACL by ETC-1002-CoA results in decreased cholesterol synthesis in the liver and lowers LDL-C in blood via upregulation of low-density lipoprotein receptors. Additionally, inhibition of ACL by ETC-1002-CoA results in concomitant suppression of hepatic fatty acid biosynthesis. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| NILEMDO Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10AX15 | C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AX Other lipid modifying agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1816051, 1816062, 1816073, 1816084, 1816095, 1816107 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 1201425002 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 61328727 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 387549 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 048721017, 048721029, 048721031, 048721043, 048721056, 048721068, 048721070, 048721082, 048721094, 048721106, 048721118 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1089830, 1089831, 1089832, 1089833, 1089834, 1089835, 1091032, 1091033, 1091034, 1091035, 1091036 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100433285 |
| Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8699228090799, 8699228090805, 8699228090812, 8699228090829, 8699228090836 |
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