This brand name is authorized in Austria, Croatia, Estonia, France, Ireland, Italy, Lithuania, Poland, Spain, Turkey, UK.
The drug NILEMDO contains one active pharmaceutical ingredient (API):
1
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UNII
1EJ6Z6Q368 - BEMPEDOIC ACID
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Bempedoic acid is an adenosine triphosphate citrate lyase (ACL) inhibitor that lowers low-density lipoprotein cholesterol (LDL-C) by inhibition of cholesterol synthesis in the liver. Bempedoic acid requires coenzyme A (CoA) activation by very long-chain acyl-CoA synthetase 1 (ACSVL1) to ETC-1002-CoA. Inhibition of ACL by ETC-1002-CoA results in decreased cholesterol synthesis in the liver and lowers LDL-C in blood via upregulation of low-density lipoprotein receptors. Additionally, inhibition of ACL by ETC-1002-CoA results in concomitant suppression of hepatic fatty acid biosynthesis. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| NILEMDO Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| C10AX15 | C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AX Other lipid modifying agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| EE | Ravimiamet | 1816051, 1816062, 1816073, 1816084, 1816095, 1816107 |
| ES | Centro de información online de medicamentos de la AEMPS | 1201425002 |
| FR | Base de données publique des médicaments | 61328727 |
| GB | Medicines & Healthcare Products Regulatory Agency | 387549 |
| IT | Agenzia del Farmaco | 048721017, 048721029, 048721031, 048721043, 048721056, 048721068, 048721070, 048721082, 048721094, 048721106, 048721118 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1089830, 1089831, 1089832, 1089833, 1089834, 1089835, 1091032, 1091033, 1091034, 1091035, 1091036 |
| PL | Rejestru Produktów Leczniczych | 100433285 |
| TR | İlaç ve Tıbbi Cihaz Kurumu | 8699228090799, 8699228090805, 8699228090812, 8699228090829, 8699228090836 |
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