This brand name is authorized in Austria, Australia, Canada, Estonia, Spain, Finland, France, Croatia, Ireland, Israel, Italy, Lithuania, New Zealand, Poland, United States
The drug ODOMZO contains one active pharmaceutical ingredient (API):
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1
Sonidegib
UNII W421AI34UW - SONIDEGIB PHOSPHATE
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Sonidegib is an orally bioavailable inhibitor of the Hh signalling pathway. It binds to Smoothened (Smo), a G protein-coupled receptor-like molecule that positively regulates the Hh pathway. Aberrant Hh signalling has been linked to the pathogenesis of several types of cancer, including basal cell carcinoma (BCC). Sonidegib binding to Smo will inhibit Hh signalling and consequently block signal transduction. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| ODOMZO Hard capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01XJ02 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XJ Hedgehog pathway inhibitors | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 11304Y |
| Country: CA | Health Products and Food Branch | Identifier(s): 02500337 |
| Country: EE | Ravimiamet | Identifier(s): 1695179, 1695180 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 1151030002 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 401494 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 65006905 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 7835 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 044480010, 044480022 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1077881, 1077884 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 19858 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100354002 |
| Country: US | FDA, National Drug Code | Identifier(s): 47335-303 |
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