ONCASPAR

This brand name is authorized in United States. It is also authorized in Austria, Brazil, Canada, Croatia, Estonia, Finland, France, Ireland, Israel, Italy, Lithuania, Netherlands, New Zealand, Poland, Romania, Spain, UK.

Active ingredients

The drug ONCASPAR contains one active pharmaceutical ingredient (API):

1	Pegaspargase UNII 7D96IR0PPM - PEGASPARGASE
	Pegaspargase is a covalent conjugate of Escherichia coli-derived L-asparaginase with monomethoxypolyethylene glycol. The mechanism of action of L-asparaginase is the enzymatic cleavage of the amino acid L-asparagine into aspartic acid and ammonia. Depletion of L-asparagine in blood results in inhibition of protein-synthesis, DNA-synthesis and RNA-synthesis, especially in leukaemic blasts which are not able to synthesise L-asparagine, thus undergoing apoptosis.
	Read more about Pegaspargase

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
ONCASPAR Solution for injection/infusion	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01XX24	Pegaspargase	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX24

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
BR	Câmara de Regulação do Mercado de Medicamentos	531319120009217, 540218100003317
CA	Health Products and Food Branch	02461900
EE	Ravimiamet	1187434, 1759361
ES	Centro de información online de medicamentos de la AEMPS	1151070002
FI	Lääkealan turvallisuus- ja kehittämiskeskus	449842, 524351
FR	Base de données publique des médicaments	61861579
GB	Medicines & Healthcare Products Regulatory Agency	378981
IL	מִשְׂרַד הַבְּרִיאוּת	8866
IT	Agenzia del Farmaco	044702013, 044702025
LT	Valstybinė vaistų kontrolės tarnyba	1079500, 1084699
NL	Z-Index G-Standaard, PRK	148644
NZ	Medicines and Medical Devices Safety Authority	18738, 21439
PL	Rejestru Produktów Leczniczych	100362958, 100403746
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W66171001, W66172001
US	FDA, National Drug Code	72694-954