This brand name is authorized in Brazil
The drug PASSAJA contains a combination of these active pharmaceutical ingredients (APIs):
1
Procaine
UNII 95URV01IDQ - PROCAINE HYDROCHLORIDE
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Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. Procaine is indicated for production of local or regional anesthesia, particularly for oral surgery. Procaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine. |
2
Thymol
UNII 3J50XA376E - THYMOL
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Thymol, a monoterpene, obtained from thyme oil or other volatile oils, is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions to help reduce and prevent plaque and gingivitis. Recently was shown, that this substance was able to significantly reduce the oxidative stress associated with cataract. The results suggested that thymol might be a potential therapeutic approach in the prevention of diabetic complications through its aldose reductase enzyme inhibitory and antioxidant activities. |
3
Menthol
UNII L7T10EIP3A - MENTHOL, UNSPECIFIED FORM
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4
Camphora
UNII N20HL7Q941 - CAMPHOR (NATURAL)
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This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: BR | Cรขmara de Regulaรงรฃo do Mercado de Medicamentos | Identifier(s): 508220050000107 |
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