This brand name is authorized in Estonia, Lithuania, Poland, Romania
The drug PRESTARIUM contains one active pharmaceutical ingredient (API):
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1
Perindopril
UNII TFT5IM1KGB - PERINDOPRIL ARGININE
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Perindopril is an inhibitor of the enzyme that converts angiotensin I into angiotensin II (Angiotensin Converting Enzyme ACE). The converting enzyme, or kinase, is an exopeptidase that allows conversion of angiotensin I into the vasoconstrictor angiotensin II as well as causing the degradation of the vasodilator bradykinin into an inactive heptapeptide. Inhibition of ACE results in a reduction of angiotensin II in the plasma, which leads to increased plasma renin activity (by inhibition of the negative feedback of renin release) and reduced secretion of aldosterone. Since ACE inactivates bradykinin, inhibition of ACE also results in an increased activity of circulating and local kallikrein-kinin systems (and thus also activation of the prostaglandin system). |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09AA04 | Perindopril | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1168275, 1168286, 1168297, 1168309, 1168310, 1168321, 1168332, 1168343, 1168354, 1168365, 1168376, 1168387, 1168398, 1168400, 1168411, 1168422, 1168433, 1168444, 1168455, 1168466, 1168477, 1168488, 1353406, 1353428, 1353439, 1353440, 1353451, 1353462, 1353473, 1353484, 1353495, 1353507, 1353518, 1353530, 1353541, 1353552, 1353563, 1353574, 1353585, 1353596, 1353608, 1353619, 1353620, 1353631, 1353664, 1353675, 1353686, 1353697, 1353709, 1353710, 1353721, 1353732, 1353743, 1353754, 1353765, 1763018, 1763029, 1763030, 1763041 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1004454, 1004455, 1018108, 1018109, 1018110, 1018111, 1018112, 1018113, 1018114, 1018115, 1018116, 1018117, 1018118, 1018119, 1018120, 1018121, 1018122, 1018123, 1018124, 1018125, 1018126, 1018127, 1018128, 1018129, 1018130, 1018131, 1018132, 1018133, 1018134, 1018135, 1018136, 1018137, 1021515, 1032846, 1032847, 1032848, 1054364, 1054365, 1054366, 1054367, 1054368, 1054369, 1054370, 1054371, 1054372, 1054373, 1054374, 1054375, 1054376, 1054377, 1054378, 1054379, 1054380, 1054381, 1054382, 1054383, 1054384, 1054385, 1054386, 1054387, 1054388, 1054389, 1054390, 1054391, 1054392, 1054393, 1084458, 1084459, 1084460, 1084461, 1084462, 1084463 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100144925, 100145190, 100145209, 100375062, 100414833, 100432021, 100443214, 100450545, 100454132, 100456710, 100457334, 100459502 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W42663001, W42664001 |
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