This brand name is authorized in Brazil, Canada
The drug PROLOPA contains a combination of these active pharmaceutical ingredients (APIs):
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1
Benserazide
UNII B66E5RK36Q - BENSERAZIDE HYDROCHLORIDE
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Benserazide (also called Serazide or Ro 4-4602) is a peripherally acting aromatic L-amino acid decarboxylase or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier. |
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2
Levodopa
UNII 46627O600J - LEVODOPA
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According to the current understanding, the symptoms of Parkinson’s disease are related to depletion of dopamine in the corpus striatum. Dopamine does not cross the blood-brain barrier. Levodopa, the precursor of dopamine, crosses the blood brain barrier and relieves the symptoms of the disease. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N04BA02 | Levodopa and decarboxylase inhibitor | N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BA Dopa and dopa derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 529204101115311, 529204102111318, 529204103118316, 529212090024203, 529212090024303, 529214080025905 |
| Country: CA | Health Products and Food Branch | Identifier(s): 00386464, 00386472, 00522597 |
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