PURI-NETHOL

This brand name is authorized in Austria, Estonia, Hong Kong, Ireland, Israel, Lithuania, Malta, Netherlands, New Zealand, Romania

Active ingredients

The drug PURI-NETHOL contains one active pharmaceutical ingredient (API):

1 Mercaptopurine UNII E7WED276I5 - MERCAPTOPURINE

Mercaptopurine is an inactive pro-drug which acts as a purine antagonist but requires cellular uptake and intracellular anabolism to thioguanine nucleotides for cytotoxicity. The mercaptopurine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. The thioguanine nucleotides are also incorporated into nucleic acids and this contributes to the cytotoxic effects of the active substance. Read about Mercaptopurine

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
PURI-NETHOL Tablet	Health Products Regulatory Authority (IE)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L01BB02	Mercaptopurine	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BB Purine analogues
Discover more medicines within L01BB02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1004971
Country: HK	Department of Health Drug Office	Identifier(s): 03770
Country: IE	Health Products Regulatory Authority	Identifier(s): 43338
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 1143
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1001642
Country: MT	Medicines Authority	Identifier(s): MA955/00802
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 183
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 6802
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W58868001