This brand name is authorized in Australia, Brazil, Canada, France, Mexico, Tunisia, Turkey
The drug PURINETHOL contains one active pharmaceutical ingredient (API):
1
Mercaptopurine
UNII E7WED276I5 - MERCAPTOPURINE
|
Mercaptopurine is an inactive pro-drug which acts as a purine antagonist but requires cellular uptake and intracellular anabolism to thioguanine nucleotides for cytotoxicity. The mercaptopurine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. The thioguanine nucleotides are also incorporated into nucleic acids and this contributes to the cytotoxic effects of the active substance. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
L01BB02 | Mercaptopurine | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01B Antimetabolites → L01BB Purine analogues |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 1598D |
Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 505613040037614 |
Country: CA | Health Products and Food Branch | Identifier(s): 00004723 |
Country: FR | Base de données publique des médicaments | Identifier(s): 63377491 |
Country: MX | Comisión Federal para la Protección contra Riesgos Sanitarios | Identifier(s): 50519 |
Country: TN | Direction de la Pharmacie et du Médicament | Identifier(s): 15493011 |
Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8699874080076 |
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