This brand name is authorized in Estonia, Croatia
The drug RAMEAM contains a combination of these active pharmaceutical ingredients (APIs):
|
1
Ramipril
UNII L35JN3I7SJ - RAMIPRIL
|
|
Ramiprilat, the active metabolite of the prodrug ramipril, inhibits the enzyme dipeptidylcarboxypeptidase I (synonyms: angiotensin-converting enzyme; kininase II). In plasma and tissue this enzyme catalyses the conversion of angiotensin I to the active vasoconstrictor substance angiotensin II, as well as the breakdown of the active vasodilator bradykinin. Reduced angiotensin II formation and inhibition of bradykinin breakdown lead to vasodilatation. |
|
2
Amlodipine
UNII 864V2Q084H - AMLODIPINE BESYLATE
|
|
Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09BB07 | Ramipril and amlodipine | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09B ACE inhibitors, combinations → C09BB ACE inhibitors and calcium channel blockers |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1712483, 1712494, 1712506, 1712517, 1712528, 1712539, 1712540, 1712551, 1712562, 1712573, 1712674, 1712685, 1712696, 1712708, 1712719, 1712720, 1712731, 1712742, 1712753, 1712764 |
| Country: HR | Agencija za lijekove i medicinske proizvode | Identifier(s): HR-H-128016330, HR-H-232568101, HR-H-459256324, HR-H-830032291 |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
