This brand name is authorized in Lithuania
The drug RAMOSTIN contains a combination of these active pharmaceutical ingredients (APIs):
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1
Rosuvastatin
UNII 83MVU38M7Q - ROSUVASTATIN CALCIUM
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Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase. Rosuvastatin increases the number of hepatic LDL receptors on the cell-surface, enhancing uptake and catabolism of LDL and it inhibits the hepatic synthesis of VLDL, thereby reducing the total number of VLDL and LDL particles. |
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2
Ramipril
UNII L35JN3I7SJ - RAMIPRIL
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Ramiprilat, the active metabolite of the prodrug ramipril, inhibits the enzyme dipeptidylcarboxypeptidase I (synonyms: angiotensin-converting enzyme; kininase II). In plasma and tissue this enzyme catalyses the conversion of angiotensin I to the active vasoconstrictor substance angiotensin II, as well as the breakdown of the active vasodilator bradykinin. Reduced angiotensin II formation and inhibition of bradykinin breakdown lead to vasodilatation. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10BX17 | C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BX Lipid modifying agents in combination with other drugs | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: LT | Valstybinฤ vaistลณ kontrolฤs tarnyba | Identifier(s): 1092993, 1092994, 1092995, 1092996, 1092997, 1092998, 1092999, 1093000, 1093001, 1093002, 1093003, 1093004, 1093005, 1093006, 1093007, 1093008 |
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