RETSEVMO

This brand name is authorized in Austria, Croatia, Estonia, Finland, France, Ireland, Italy, Lithuania, Poland, Romania, Spain, UK.

Active ingredients

The drug RETSEVMO contains one active pharmaceutical ingredient (API):

1	Selpercatinib UNII CEGM9YBNGD - SELPERCATINIB
	Selpercatinib is an inhibitor of the rearranged during transfection (RET) receptor tyrosine kinase. Selpercatinib inhibited wild-type RET and multiple mutated RET isoforms as well as VEGFR1 and VEGFR3 with IC50 values ranging from 0.92 nM to 67.8 nM. In in vitro and in vivo tumor models, selpercatinib demonstrated anti-tumor activity in cells harboring constitutive activation of RET protein resulting from gene fusions and mutations, including CCDC6-RET, KIF5B-RET, RET V804M, and RET M918T.
	Read more about Selpercatinib

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
RETSEVMO Hard capsule	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01EX22		L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01E Protein kinase inhibitors → L01EX Other protein kinase inhibitors
Discover more medicines within L01EX22

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EE	Ravimiamet	1842511, 1842522, 1842533
ES	Centro de información online de medicamentos de la AEMPS	1201527001, 1201527002
FI	Lääkealan turvallisuus- ja kehittämiskeskus	451289, 452618, 464989, 495704
FR	Base de données publique des médicaments	61648467, 66580529
GB	Medicines & Healthcare Products Regulatory Agency	394207, 394210
IT	Agenzia del Farmaco	049358017, 049358029, 049358031, 049358043, 049358056, 049358068, 049358070, 049358082, 049358094, 049358106, 049358118
LT	Valstybinė vaistų kontrolės tarnyba	1092128, 1092129, 1092130, 1092963, 1092964, 1092965, 1092966, 1092967, 1092968, 1092969, 1092970
PL	Rejestru Produktów Leczniczych	100448387, 100448393
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W67513001, W67513002, W67514001, W67514002, W67514003