This brand name is authorized in Austria, Cyprus, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, United Kingdom, United States
The drug SIKLOS contains one active pharmaceutical ingredient (API):
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1
Hydroxycarbamide
UNII X6Q56QN5QC - HYDROXYUREA
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One of the mechanisms by which hydroxycarbamide acts is the elevation of foetal haemoglobin (HbF) concentrations in sickle cell patients. In addition hydroxycarbamide causes an immediate inhibition of DNA synthesis by acting as a ribonucleotide reductase inhibitor, without interfering with the synthesis of ribonucleic acid or protein. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| SIKLOS Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01XX05 | Hydroxycarbamide | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1304558, 1521009, 1521010, 1521021 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 07397001, 07397002 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 162865, 371181 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 66384911, 66898948 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 139565, 193138 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 045338011, 045338023, 045338035, 045338047 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1030739, 1059505, 1059506, 1059507 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 85855, 96911 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100033054, 100316585 |
| Country: US | FDA, National Drug Code | Identifier(s): 71770-100, 71770-105, 71770-120 |
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