This brand name is authorized in Austria, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Lithuania, Netherlands, Poland, United Kingdom
The drug SKILARENCE contains one active pharmaceutical ingredient (API):
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1
Dimethyl fumarate
UNII FO2303MNI2 - DIMETHYL FUMARATE
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The anti-inflammatory and immunomodulating effects of dimethyl fumarate and its metabolite monomethyl fumarate are not fully elucidated but are thought to be mainly due to the interaction with the intracellular reduced glutathione of cells directly involved in the pathogenesis of psoriasis. Their main activity is considered to be immunomodulatory, resulting in a shift in T helper cells (Th) from the Th1 and Th17 profile to a Th2 phenotype. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| SKILARENCE Gastro-resistant tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L04AX07 | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1748730, 1748741, 1748752, 1748763, 1748774, 1748785, 1748796, 1748808, 1748819, 1748820, 1748831, 1798218, 1826131, 1826142 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 1171201001, 1171201004 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 055280, 565497, 575978 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 62607886, 62691126 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 346864, 346866, 346869, 389228 |
| Country: IE | Health Products Regulatory Authority | Identifier(s): 88933, 88934, 88935 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 045493018, 045493020, 045493032, 045493044, 045493057, 045493069, 045493071, 045493083, 045493095, 045493107, 045493119, 045493121, 045493133, 045493145 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1083253, 1083254, 1083255, 1083256, 1083257, 1083258, 1083259, 1083260, 1083261, 1083262, 1083263, 1085906, 1088419, 1088420 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 109010, 109118 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100392110, 100392132 |
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