SKILARENCE

This brand name is authorized in Austria, Croatia, Estonia, Finland, France, Ireland, Italy, Lithuania, Netherlands, Poland, Spain, UK.

Active ingredients

The drug SKILARENCE contains one active pharmaceutical ingredient (API):

1	Dimethyl fumarate UNII FO2303MNI2 - DIMETHYL FUMARATE
	The anti-inflammatory and immunomodulating effects of dimethyl fumarate and its metabolite monomethyl fumarate are not fully elucidated but are thought to be mainly due to the interaction with the intracellular reduced glutathione of cells directly involved in the pathogenesis of psoriasis. Their main activity is considered to be immunomodulatory, resulting in a shift in T helper cells (Th) from the Th1 and Th17 profile to a Th2 phenotype.
	Read more about Dimethyl fumarate

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
SKILARENCE Gastro-resistant tablet	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L04AX07		L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants
Discover more medicines within L04AX07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
EE	Ravimiamet	1748730, 1748741, 1748752, 1748763, 1748774, 1748785, 1748796, 1748808, 1748819, 1748820, 1748831, 1798218, 1826131, 1826142
ES	Centro de información online de medicamentos de la AEMPS	1171201001, 1171201004
FI	Lääkealan turvallisuus- ja kehittämiskeskus	055280, 565497, 575978
FR	Base de données publique des médicaments	62607886, 62691126
GB	Medicines & Healthcare Products Regulatory Agency	346864, 346866, 346869, 389228
IE	Health Products Regulatory Authority	88933, 88934, 88935
IT	Agenzia del Farmaco	045493018, 045493020, 045493032, 045493044, 045493057, 045493069, 045493071, 045493083, 045493095, 045493107, 045493119, 045493121, 045493133, 045493145
LT	Valstybinė vaistų kontrolės tarnyba	1083253, 1083254, 1083255, 1083256, 1083257, 1083258, 1083259, 1083260, 1083261, 1083262, 1083263, 1085906, 1088419, 1088420
NL	Z-Index G-Standaard, PRK	109010, 109118
PL	Rejestru Produktów Leczniczych	100392110, 100392132